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Thyroid Profile Total (T3, T4, TSH)

Thyroid Profile Total (T3, T4, TSH) STARTING FROM ONLY ₹450*

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About The Thyroid Gland

The thyroid gland, often likened to a butterfly or bowtie, comprises two lobes connected by a thin bridge of tissue called the isthmus. Situated just below the Adam’s apple, the thyroid gland is nestled against the windpipe (trachea) and adjacent to the larynx. Within its confines, the thyroid gland houses millions of microscopic structures known as thyroid follicles. These follicles are lined with specialised cells called follicular cells, which are responsible for producing and secreting thyroid hormones.

Function Of The Thyroid Gland

At the heart of the thyroid’s function lie its hormones—thyroxine (T4) and triiodothyronine (T3). These hormones, synthesised within the follicular cells, orchestrate a symphony of metabolic processes throughout the body. Thyroxine (T4), the primary hormone secreted by the thyroid gland, serves as a precursor to triiodothyronine (T3). Once released into the blood, T4 gets converted to T3, the more metabolically active form of thyroid hormone.

Understanding The Two Main Thyroid Hormones: T3 & T4

Triiodothyronine (T3) and thyroxine (T4) are two key hormones secreted by the thyroid gland, each bearing distinct roles in orchestrating metabolic processes throughout the body. T4, named for its four iodine atoms, serves as the primary hormone synthesised by the thyroid follicular cells. Meanwhile, T3, with three iodine atoms, is a more potent and metabolically active form of thyroid hormone, derived from the conversion of T4 within tissues. The production of T3 and T4 is tightly regulated by feedback mechanisms involving the hypothalamus, pituitary gland, and thyroid gland, collectively known as the hypothalamic-pituitary-thyroid (HPT) axis. When levels of T3 and T4 decrease in the bloodstream, the hypothalamus releases thyrotropin-releasing hormone (TRH), stimulating the pituitary gland to release thyroid-stimulating hormone (TSH). In turn, TSH prompts the thyroid gland to increase the synthesis and secretion of T3 and T4. Conversely, elevated levels of T3 and T4 inhibit the release of TRH and TSH, thereby maintaining hormonal balance.

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Roles and Functions

T3 and T4 exert profound effects on nearly every tissue and organ in the body, influencing metabolism, growth, development, and thermoregulation. T4 serves as a reservoir of thyroid hormone, with the majority of circulating T3 derived from peripheral conversion of T4 to T3 by deiodinase enzymes. While T4 exhibits a longer half-life and acts as a precursor to T3, T3 is the more biologically active hormone, binding to thyroid hormone receptors within cells and modulating gene expression to regulate metabolic rate, protein synthesis, and energy expenditure.

What Are The Components Of Thyroid Profile Total Test?

Thyroxine (T4)

Thyroxine is the primary hormone produced by the thyroid gland. It plays a crucial role in regulating metabolism, growth, and energy levels in the body. Thyroid Profile Total measures the total amount of T4 in the blood, including both bound and free forms.

Triiodothyronine (T3)

Triiodothyronine is another important thyroid hormone that helps regulate metabolism and energy production. Thyroid Profile Total assesses the total amount of T3 present in the bloodstream.

Thyroid-Stimulating Hormone (TSH)

TSH is produced by the pituitary gland and stimulates the thyroid gland to produce T4 and T3. Elevated levels of TSH may indicate an underactive thyroid (hypothyroidism), while low levels may suggest an overactive thyroid (hyperthyroidism).

Who Should Get Tested?

Individuals with risk factors such as a family history of thyroid disorders, autoimmune conditions, or previous thyroid surgery may undergo routine screening to detect any abnormalities early on. Individuals might also need thyroid function tests if they exhibit symptoms of hyperthyroidism (an overactive thyroid) or hypothyroidism (an underactive thyroid). Book a Thyroid Profile Total in Sikandra for ONLY ₹100*

Book a Thyroid Profile Total in Sikandra for ONLY ₹450*

How To Prepare For The Test?

Preparing for thyroid function tests involves a few simple steps to ensure accurate results. Firstly, inform your healthcare provider about any medications or supplements you’re taking, as some can affect thyroid hormone levels. Fasting overnight before the test is recommended, although drinking water is usually allowed. Avoiding strenuous exercise, excessive alcohol consumption, and adhering to any specific instructions from your healthcare provider can help ensure reliable test results. By following these guidelines, you can facilitate an accurate assessment of your thyroid function.

Book a Thyroid Profile Total in Sikandra for ONLY ₹450*

How To Interpret The Test Results?

What Is The Normal Range For Thyroid Hormones?

ParameterNormal RangeUnits
T30.97-1.80ng/mL
T45.53-14.00ug/dL
TSH0.46-4.68uIU/ml

Thyroxine (T4)

Thyroxine is the primary hormone produced by the thyroid gland. It plays a crucial role in regulating metabolism, growth, and energy levels in the body. Thyroid Profile Total measures the total amount of T4 in the blood, including both bound and free forms.

Triiodothyronine (T3)

Triiodothyronine is another important thyroid hormone that helps regulate metabolism and energy production. Thyroid Profile Total assesses the total amount of T3 present in the bloodstream.

Thyroid-Stimulating Hormone (TSH)

TSH is produced by the pituitary gland and stimulates the thyroid gland to produce T4 and T3. Elevated levels of TSH may indicate an underactive thyroid (hypothyroidism), while low levels may suggest an overactive thyroid (hyperthyroidism).