Direct Coombs Test in Gurgaon

Direct Coombs Test in Gurgaon

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One of the most crucial parts of the body’s immune system is the presence of antibodies that fight against various germs in the body. However, under certain circumstances, the antibodies might end up attacking the healthy blood cells in the bloodstream. The Coombs Test in Gurgaon is used to detect the presence of antibodies that might be targeting red blood cells. The test is also known as the antiglobulin test or red blood cell antibody screening test.

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About Direct Coombs Test

Why is the Direct Coombs test done?

A Direct Coombs Test is helpful if the person is not feeling so well or experiencing any symptoms that might point towards blood disorders. A certain blood disease by the name of autoimmune haemolytic anaemia could be the reason for this. In this condition, antibodies destroy red blood cells faster than the body can produce them. This disease could enter the body due to:

  • Certain diseases like Lupus or Leukaemia
  • Certain infections such as Mononucleosis
  • Using certain medication such as Penicillin

New-born babies that show yellowish skin or eye conditions could be suffering from haemolytic disease of the new-born or HDN. This could happen due to improper mixing of the parents’ blood types.

What does the Direct Coombs test measure?

Antibodies are a crucial part of the body’s immune system. These antibodies are proteins that are released in response to foreign substances (like germs or bacteria). These antibodies bind with the substances, destroying them. However, due to certain disorders in the blood, the antibodies might end up attacking the red blood cells. In that case, the body is not able to produce enough red blood cells to function. That could lead to fatal diseases in humans.

The Direct Coombs Test is also known as the Direct Antiglobulin Test or DAT. This is performed by adding anti-human globulin to the patient’s red blood cells. In this case, the presence of anti-RBC antibodies causes the red blood cells to be agglutinated (firmly stuck together). In DAT, agglutination occurs when the anti-RBC antibody bound to antigen links with anti-human globulin introduced externally. A doctor should be contacted after the test results are seen.

Risk/Side-effects of Direct Coombs test

Generally, there is very less risk of any major symptoms inside the body. The person might feel slight pain (or some bruising) in the area where the needle has been pierced to take the blood. But those tend to disappear pretty quickly and not cause any major problems to the patient. In very rare cases, the patient might develop blood collection under the skin or infection at the site where the needle was pierced. But that is a very rare occurrence and nothing major to worry about.


Why should you choose's testing services? offers state-of-the-art facilities to patients looking to get their lab results quickly and accurately. Their technicians are trained to draw blood without causing any sort of injury to the patient. The technicians working on testing are experienced in the field of gathering the samples correctly and delivering the reports on time. If you want to opt for the best Direct Coombs test in Gurgaon, look no further than The website contains all the information that you will need for a safe testing experience.



Are there any preparations needed for this test?

There are no major preparations needed for the test (preferably stay empty stomach before the test).

How is the sample taken?

The blood is taken from the arm. The area is cleaned with rubbing alcohol, and the technician takes blood precisely.


Are there any risks to the test?

There are minor risks that do not happen under general circumstances. The technicians just need to be a little careful.


How does the body get rid of antibodies?

It requires external treatment through various processes.

Interpreting the Direct Coombs Test Results

Interpreting the Direct Coombs Test Results

The normal result obviously means no detection of anti-RBC antibodies inside the body. This indicates that there is no clumping (agglutination) of cells. The range varies for certain laboratories, but they are more or less the same.

Abnormalities in the test could be an indication of the antibodies attacking the red blood cells. That could happen due to:

  • Autoimmune Haemolytic Anaemia
  • Chronic Lymphocytic Leukaemia
  • Blood disease in new-born babies
  • Infectious Mononucleosis
  • Mycoplasma infection
  • Syphilis
  • Lupus
  • Improper reaction to a blood transfusion

The test could show abnormalities due to certain other reasons (that are unexplained), especially in older people.

The next step to getting a positive result on the antibody screening is the identification of the antibody. Antibody removal can be a difficult process in individuals, but there are various treatments in hand to treat such a condition. Antibodies could result from certain vaccinations or blood transfusions being done in individuals.

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Steps to Book a Direct Coombs Test for Home Collection in Gurgaon

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