Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test in Hyderabad

Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test in Hyderabad

Looking to book an Apolipoprotein A and B test in Hyderabad? Read below to find out about apolipoproteins.

Apolipoproteins are the proteins that are used for carrying or transporting lipids through the bloodstream. Lipids are fats, starch and cholesterol which do not dissolve in the blood, and, as such, need to be transported. Apolipoproteins combine with lipids and then carry them to various cells. They also help in maintaining cholesterol levels. An imbalance in the normal concentrations of Apolipoproteins can indicate a risk of cardiovascular diseases. Therefore, these tests are most often ordered along with other lipid tests or complete lipid profiles.

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About Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test

Why is the Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test done?

The Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test is done to check for the risk of cardiovascular diseases. Additionally, the doctor may also order the test to see the effectiveness of any lipid treatments that the patient may be undergoing. This would help in deciding the further course of action: whether the treatment should be continued or changed.

What does the Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test measure?

Apolipoprotein B is the major protein component in low-density lipoproteins, commonly known as bad cholesterol. Apolipoprotein A1, on the other hand, is the primary protein component in High-Density Lipoprotein, commonly known as good cholesterol. This test is used to measure the ratio of these two Apolipoproteins in the blood to know whether a healthy balance is maintained or not. If Apolipoprotein B is higher than Apolipoprotein A1, then the patient is at a higher than normal risk of developing cardiovascular diseases.

Risks/side effects of Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test

This test has no real risks or side effects as it is done through a simple blood draw. However, the patient may feel pain in the arm (the blood is drawn from the arm), or experience bruising where the needle is pricked, or in rare cases, may even experience hematoma. He/she may also feel dizzy or lightheaded right after the blood is drawn out.


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Are any special preparations required for this test?

There are no special preparations needed for this test.

When should I consult a doctor for this test?

Patients who have a history of heart disease in their family and have high cholesterol must consult their doctor.

Can the problematic underlying issues for abnormal results be fixed?

Making lifestyle changes, like exercising and eating healthy, may help control the level of cholesterol; however, it depends on individual patients.

Can I get this test done for a regular checkup?

This test is not recommended for a regular checkup or widespread checking. It must only be done when asked for by the doctor.

Interpreting Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test Results

Interpreting Apolipoprotein B: Apolipoprotein A1 (APO B: APO A­1) Ratio Test Results

The results of this test may be considered, along with additional tests and the patient’s family history. A normal ratio between the two kinds of proteins shows that the patient is not at risk for cardiovascular disease. However, if Apolipoprotein B is in a higher ratio than Apolipoprotein A1, it can indicate a high risk of atherosclerotic cardiovascular disease. On the other hand, lower levels would indicate the possibility of polyneuropathy.

If the levels of Apolipoprotein A1 protein are low, it can point towards coronary artery disease. If the levels are extremely low, it can indicate a genetic issue or liver disease.

Ratio of APO B:APO A1 Indication Health Risk
APO B> APO A1 High APO B levels, 

Low APO A1 levels. 

Cardiovascular disease, Coronary artery disease, liver disease
APO B< APO A1 Low APO B levels, 

High APO A1 levels


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