The CD19, or clusters of differentiation 19, or B-lymphocyte antigen CD19 test is prescribed by doctors when they suspect that the patient might be suffering from cancers that arise from the B-cells of the white blood cells. The CD19 test in Kolkata is used as an individual marker that identifies the presence of surface antigen of the B-lymphocyte. This test helps not only to identify the presence of a disorder, but also to monitor the progress of immunotherapies.
B-cells are white blood cells that are a type of lymphocyte. The main role of these B-cells or B-lymphocytes is to produce antibodies in response to antigens that are released by foreign pathogens. Unlike other types of antibodies, the B-cells do not secrete antibodies, but insert them into the plasma membrane. B-cells contain B cell receptors that enable the cells to bind with the foreign antigen that helps suppress the illness.
Clinical oncology relies on the specific biomarker called CD19 to check for B-cell-related conditions. Being a hallmark for testing this lymphocyte, CD19 is always prescribed to confirm if the person is suffering from the following disorders:
The process used to check for CD 19 is known as flow cytometry. Flow cytometry is a technique that provides rapid analysis of the presence of a higher number of cells at a single-cell level. The principle used in flow cytometry is that when a laser hits the cells, light scattering and fluorescence emission occur.
CD19 is a protein that helps establish the signaling thresholds for the B-cells, as CD19 modulates the dependent and independent BCR.
The test is suggested when the following symptoms are observed:
The CD19 test also specifically helps identify that B-lymphocytes are causing the problems and not T-cells or granulocytes.
The flow cytometry technique requires blood samples from the patient. The process of collecting blood is called venipuncture (when drawn from the veins) and this technique is safe and painless. An experienced phlebotomist does know how to quickly and effectively draw blood from the vein.
Blood collection poses no threats to health, but some people might suffer from weakness or experience itching around the area from where the blood was drawn. These side effects usually go away on their own.
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When there is a deficiency of the CD19 protein, the patient might not show any symptoms immediately, but B-cells are not activated with haste when B cell receptors are signaling.
Doctors can suggest erythropoietin sedimentation rate or complete blood count along with these biomarker tests.
Yes, the CD19 biomarker also helps detect immature B-cells.
The test will yield either a positive result or a negative result. When the result is positive, the doctor might suggest more biomarker tests or hemogram tests to know the current physiology of the patient and then plan for a treatment that will help the patient to become better.
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